Smith tossed a 4-yard touchdown pass to Brett Swain on the opening possession, backup Colin Kaepernick ran 78 yards for a score on the next and the 49ers breezed past the Minnesota Vikings 17-6 Friday.
Christian Ponder completed 4 of 9 passes for 80 yards, and Toby Gerhart ran for 31 yards for Minnesota (No. 29) in place of rehabbing starter Adrian Peterson. The Vikings offense showed promise everywhere but in the end zone, settling for field goals of 39 and 26 yards by new kicker Blair Walsh in Candlestick Park's whipping winds.
Randy Moss made his 49ers debut after sitting out last season, though it was hard to notice. The 35-year-old wide receiver, who signed a one-year deal with San Francisco, was never targeted.
Jacobs, who signed a one-year deal with San Francisco after winning his second Super Bowl with New York, showed his strength in short-yardage situations - a missing element for the 49ers last season - by running for 3 yards on fourth-and-1 from San Francisco's 47 to extend the opening drive. He added a 23-yard sprint and finished with 31 yards rushing.
San Francisco also received rushes of 19 yards by Cartwright and 14 by Hunter to set up Smith's short fade to Swain that finished off the first-team's only possession. The 13-play, 68-yard drive lasted 6:07 and resembled the kind of grind-it-out fight that helped the 49ers to a 13-3 regular season last year and the franchise's first playoff appearance in a decade.
MIAMI - The Tampa Bay Buccaneers got off to a good start under new coach Greg Schiano, scoring touchdowns on their first two possessions in a 20-7 preseason win over the Miami Dolphins on Friday night.
Starting quarterback Josh Freeman left the game after playing only one series for Tampa Bay (No. 26 in the AP Pro32), but completed 4 of 5 passes for 41 yards. LeGarrette Blount finished off the drive with a 1-yard touchdown plunge on fourth-and-goal.
N.Y. Giants 31
JACKSONVILLE, Fla. - The Jacksonville Jaguars' starting unit faded after a fast start. The New York Giants were the opposite, scoring on four consecutive series after being stopped on their opening drive.
Eli Manning only played two series and produced three points before taking the rest of the night off in the Giants' 32-21 loss in both teams' preseason opener. New York (No. 3 in the AP Pro32) built a 17-point first half lead, but Jacksonville (No. 31 in the AP Pro32) responded with an 18-point second half to earn the victory.
Manning was 4 of 8 for 60 yards and a passer rating of 75.0.
Jacksonville quarterback Blaine Gabbert was sharp in directing an 89-yard touchdown drive in 13 plays on the Jaguars' first series.